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Taken together, the data from this experiment demonstrates that marginally increasing total GLP1 is not sufficient to protect against olanzapine-induced metabolic disturbances and that more robust increases in total and/or active GLP1 may be required to blunt the metabolic consequences of acute olanzapine treatment

Compound Reference Data Compound: AOD-9604 CAS Number: 221231-10-3 Molecular Formula: C78H123N23O23S2 Molecular Weight: 1815.07 g/mol Sequence: YLRIVQCRSVEGSCGF (residues 177191 of human growth hormone) Synonyms: AOD9604, Anti-Obesity Drug 9604, hGH fragment 176-191 (modified) Selected Published Studies Published research on AOD-9604 consists of animal-model and in vitro studies

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This bidirectional regulation suggests sophisticated sensing of tissue microenvironmental cues, enabling GHK-Cu to normalize MMP activity toward homeostatic levels rather than exerting uniform stimulatory or inhibitory effects